Applications

LOCTITE® 4601™ – Medical device assembly adhesive with low odor, low bloom, bonds plastics and metals.

  • Item Name: LOCTITE® 4601™
  • Manufacturer: Henkel
  • Product Category: Instant Adhesives
  • Technologies: Cyanoacrylate (Alkoxyethyl cyanoacrylate)
  • Applications: Bonding metals, plastics, and elastomers; ideal for assembling disposable medical devices where vapor control is challenging
  • Color: Transparent, colorless to light yellow liquid
  • Cure Type: Humidity cure
  • Package Size: Contact Techniq VN for details
  • Shelf Life: Contact Techniq VN for details

1. Product Overview

LOCTITE® 4601™ is a medium-viscosity, low-odor, and low-blooming cyanoacrylate adhesive with excellent bonding performance on metals, plastics, and elastomers. It is particularly suitable for applications requiring vapor control and is compliant with ISO 10993 biocompatibility standards for medical device assembly.

2. Applications

  • Bonding metals, plastics, and elastomers
  • Suitable for medical device assembly (ISO 10993 compliance)
  • Ideal for applications requiring low odor and minimal blooming

3. Typical Properties

Uncured Properties

Property Value
Chemical Type Alkoxyethyl cyanoacrylate
Appearance Transparent, colorless to light yellow liquid
Specific Gravity @ 25°C 1.1
Viscosity (Brookfield LVF, Spindle 1, 30 rpm) 30 to 60 mPa·s

Curing Performance

  • Cure Speed vs. Substrate (Fixture time at 22°C / 50% RH)
    • Steel: 30-70 sec
    • Aluminum: 5-20 sec
    • Zinc Dichromate: 60-180 sec
    • Rubber (Neoprene, Nitrile): <5 sec
    • ABS, PVC, Polycarbonate: 20-60 sec
  • Cure Speed vs. Environmental Factors
    • Faster curing in high humidity
    • Thinner bond gaps lead to higher cure speeds

Cured Properties (After 24 Hours @ 22°C)

Property Value
Glass Transition Temperature (Tg) 130°C
Thermal Conductivity 0.1 W/(m·K)
Coefficient of Thermal Expansion 80 × 10⁻⁶ K⁻¹

Electrical Properties

Property Value
Volume Resistivity 10Ù¹⁵ Ω·cm
Surface Resistivity 10Ù¹⁵ Ω
Dielectric Breakdown Strength 25 kV/mm

Adhesive Performance (Lap Shear Strength @ 22°C, N/mm²)

Substrate Strength (N/mm²)
Steel 14-22
Aluminum 9-15
Zinc Dichromate 4-10
ABS 6-20
PVC 2-8
Polycarbonate 3-10
Phenolic 5-15
Neoprene/Nitrile 5-15

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